Ingredients | Percent of gliclazide release (n = 3)% | ||||||||
No | K15 | E15 | DCP | Drug Content% | |||||
(mg) | (mg) | (mg) | 1 h | 2 h | 4 h | 6 h | 8 h | ||
RP | - | - | - | 100 | 12.41 | 30.59 | 53.38 | 73.60 | 88.39 |
N1 | 10 | 10 | 10 | 105 | 20.27 | 61.96 | 90.63 | 100.00 | - |
N2 | 20 | 10 | 10 | 104.34 | 16.33 | 22.04 | 41.20 | 55.78 | 68.02 |
N3 | 10 | 30 | 10 | 99.09 | 22.34 | 48.37 | 87.13 | 100.00 | - |
N4 | 10 | 10 | 50 | 98.07 | 19.87 | 43.99 | 63.44 | 100.00 | - |
N5 | 20 | 10 | 50 | 103.09 | 11.95 | 21.77 | 40.36 | 57.89 | 70.27 |
N6 | 10 | 30 | 50 | 104.88 | 21.59 | 39.93 | 79.19 | 100.00 | - |
N7 | 20 | 30 | 50 | 99.18 | 12.40 | 21.38 | 38.32 | 55.39 | 71.09 |
N8 | 10 | 30 | 23.5 | 100.94 | 22.62 | 46.39 | 80.44 | 100.00 | - |
N9 | 10 | 30 | 36.5 | 97.20 | 26.64 | 53.44 | 91.39 | 100.00 | - |
N10 | 10 | 16.5 | 10 | 96.13 | 24.12 | 81.19 | 100.00 | - | - |
N11 | 10 | 23.5 | 10 | 102.79 | 17.45 | 41.32 | 84.80 | 100.00 | - |
N12 | 13.5 | 30 | 10 | 104.96 | 13.50 | 31.24 | 55.03 | 77.23 | 87.77 |
N13 | 20 | 20 | 30 | 103.42 | 11.34 | 29.27 | 49.02 | 66.64 | 81.17 |
N14 | 15 | 10 | 30 | 101.04 | 22.12 | 30.24 | 58.34 | 79.21 | 96.06 |
N15 | 15 | 20 | 50 | 104.98 | 18.98 | 37.66 | 63.80 | 81.63 | 99.02 |
N16 | 15 | 20 | 30 | 103.02 | 16.28 | 33.10 | 61.02 | 80.11 | 98.85 |
N17 | 15 | 20 | 30 | 102.20 | 17.58 | 43.79 | 73.18 | 98.86 | 100.00 |
N18 | 15 | 20 | 30 | 100.76 | 14.23 | 32.22 | 65.07 | 86.25 | 98.12 |
N19 | 15 | 20 | 30 | 97.24 | 18.68 | 37.85 | 65.13 | 84.02 | 95.19 |